Iptacopan (LNP023)

Catalog No.: A18905
Factor B inhibitor
LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM).
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Product Name Price Stock Qty
LNP023 5mg
Special Price $280.00 Regular Price $350.00
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LNP023 10mg
Special Price $520.00 Regular Price $650.00
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LNP023 50mg
Special Price $1,440.00 Regular Price $1,800.00
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Adooq Products cited in reputable paper
Adooq's Iptacopan (LNP023) has been cited by 1 publications
  • Wenbin Yang, .et al. , J Clin Invest, 2022, Oct 17;132(20):e157975 PMID: 36250462
  • Biological Activity
    Discription LNP023 is a highly potent factor B (FB) inhibitor with an IC50 value of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human FB (KD=7.9 nM).
    Product Information
    Catalog Num A18905
    Formula C25H30N2O4
    Molecular Weight 422.52
    CAS Number 1644670-37-0
    SMILES O=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1
    Synonyms LNP 023, LNP-023
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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