Lonafarnib (SCH66336)
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. | ||
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Catalog Num | A12328 |
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Formula | C27H31Br2ClN4O2 |
Molecular Weight | 638.82 |
CAS Number | 193275-84-2 |
SMILES | C1CN(CCC1CC(=O)N2CCC(CC2)[C@@H]3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N |
Synonyms | Sarasar, SCH 66336, SCH66336, SCH-66336 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 116 mg/mL (181.58 mM) | |
Water | Insoluble | ||
Ethanol | 116 mg/mL (181.58 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 15.65 mL | 78.27 mL | 156.54 mL |
0.5 mM | 3.13 mL | 15.65 mL | 31.31 mL |
1 mM | 1.57 mL | 7.83 mL | 15.65 mL |
5 mM | 0.31 mL | 1.57 mL | 3.13 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2