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- Stella Liong,et al. Placental Ras Regulates Inflammation Associated with Maternal Obesity, Mediators Inflamm, 2018, 2018: 3645386 30402038
|Storage||at -20°C 3 years Powder|
|Synonyms||Sarasar, SCH 66336, SCH66336, SCH-66336|
|SMILES code||C1CN(CCC1CC(=O)N2CCC(CC2)[[email protected]@H]3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N|
|Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.|
|Solubility (25°C)*||In vitro||DMSO||127 mg/mL (198.8 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||127 mg/mL (198.8 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||15.65 mL||78.27 mL||156.54mL|
|0.5 mM||3.13 mL||15.65 mL||31.31 mL|
|1 mM||1.57 mL||7.83 mL||15.65 mL|
|5 mM||0.31 mL||1.57 mL||3.13 mL|
*The above data is based on the productmolecular weight 638.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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