Lucidenic acid O acts as a potent inhibitor of DNA polymerases, targeting calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase. Its inhibitory activity is characterized by IC50 values of 42 μM, 99 μM, and 69 μM, respectively. This compound is valuable for research applications focusing on DNA replication and viral infections, offering insights into the mechanisms of polymerase inhibition.
Lucidenic acid O acts as a potent inhibitor of DNA polymerases, targeting calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase. Its inhibitory activity is characterized by IC50 values of 42 μM, 99 μM, and 69 μM, respectively. This compound is valuable for research applications focusing on DNA replication and viral infections, offering insights into the mechanisms of polymerase inhibition.
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