Lurbinectedin

Catalog No.: A18237

Lurbinectedin

Lurbinectedin Chemical Structure

CAS NO. 497871-47-3

Lurbinectedin (PM01183) is a new DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.

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1 mg
$1,600.00
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Biological Activity

Lurbinectedin (PM01183) is a new DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.74 mL 63.7 mL 127.41 mL
0.5 mM 2.55 mL 12.74 mL 25.48 mL
1 mM 1.27 mL 6.37 mL 12.74 mL
5 mM 0.25 mL 1.27 mL 2.55 mL

*The above data is based on the productmolecular weight 784.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18237
M. Wt 784.88
Formula C41H44N4O10S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 497871-47-3
Synonyms Lurbinectedin; PM01183; PM-01183; UNII-2CN60TN6ZS
SMILES Cc1cc2c(c(c1OC)O)[[email protected]@H]3[[email protected]@H]4[[email protected]]5c6c(c7c(c(c6OC(=O)C)C)OCO7)[[email protected]@H](N4[[email protected]]([[email protected]](C2)N3C)O)COC(=O)[[email protected]@]8(CS5)c9c(c1cc(ccc1[nH]9)OC)CCN8

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