LY 3200882

Catalog No.: A16816

TGFβRI inhibitor

LY 3200882 Chemical Structure

CAS NO. 1898283-02-7

LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.

Availability: In stock

Package Price Qty
2 mg
$60.00
5 mg
$110.00
10 mg
$180.00
50 mg
$580.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.96 mL 114.81 mL 229.61 mL
0.5 mM 4.59 mL 22.96 mL 45.92 mL
1 mM 2.3 mL 11.48 mL 22.96 mL
5 mM 0.46 mL 2.3 mL 4.59 mL

*The above data is based on the productmolecular weight 435.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16816
Actions Inhibitor
M. Wt 435.52
Formula C24H29N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1898283-02-7
Synonyms LY-3200882, LY3200882
SMILES CC(O)(C)C1=NC=CC(NC2=NC=CC(OC3=CN(C4CC4)N=C3C5CCOCC5)=C2)=C1

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