LY 3200882

Name: LY 3200882
SKU: A16816
Price: 30 USD
Rating: 5 (288 reviews)

Catalog No.: A16816

TGFβRI inhibitor

LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.

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Grouped product items
Size	Price	Stock
1mg	$30.00	In stock
2mg	$55.00	In stock
5mg	$80.00	In stock
10mg	$140.00	In stock
25mg	$280.00	In stock
50mg	$450.00	In stock
100mg	$680.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription	LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.

Product Information

Catalog Num	A16816
Formula	C24H29N5O3
Molecular Weight	435.52
CAS Number	1898283-02-7
SMILES	CC(O)(C)C1=NC=CC(NC2=NC=CC(OC3=CN(C4CC4)N=C3C5CCOCC5)=C2)=C1
Synonyms	LY-3200882, LY3200882
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	79 mg/mL (181.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.96 mL	114.81 mL	229.61 mL
0.5 mM	4.59 mL	22.96 mL	45.92 mL
1 mM	2.3 mL	11.48 mL	22.96 mL
5 mM	0.46 mL	2.3 mL	4.59 mL

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