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Lys05

Autophagy inhibitor

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Catalog No. A16358

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Lys05 5mg A16358-5
$90.00
Lys05 10mg A16358-10
$140.00
Lys05 50mg A16358-50
$420.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ.

Lys05

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Chemical Information

Catalog Num A16358
Actions Inhibitor
M. Wt 440.37
Formula C23H23Cl2N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1391426-22-4
Synonyms Lys-05, Lys 05
SMILES CN(CCNC1=CC=NC2=CC(Cl)=CC=C12)CCNC3=CC=NC4=CC(Cl)=CC=C34

Biological Activity

Description
Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.71 mL 113.54 mL 227.08mL
0.5 mM 4.54 mL 22.71 mL 45.42 mL
1 mM 2.27 mL 11.35 mL 22.71 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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