m-PEG12-Thiol

Catalog No.: A82644
PROTAC Linkers
m-PEG12-Thiol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the formation of stable linkages between target proteins and E3 ligases, promoting ubiquitination and subsequent protein degradation. It is particularly valuable in the development of targeted protein degradation strategies for research applications in cancer, neurodegenerative diseases, and other therapeutic areas.
Grouped product items
Size Price Stock Qty
50mg
$125.00
In stock
100mg
$185.00
In stock
250mg
$295.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionm-PEG12-Thiol is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the formation of stable linkages between target proteins and E3 ligases, promoting ubiquitination and subsequent protein degradation. It is particularly valuable in the development of targeted protein degradation strategies for research applications in cancer, neurodegenerative diseases, and other therapeutic areas.
Product Information
Catalog NumA82644
FormulaC25H52O12S
Molecular Weight576.74
CAS Number2413368-61-1
SMILESSCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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