m-PEG24-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. Its unique reactivity enables the efficient conjugation of various biomolecules, facilitating the development of targeted degradation strategies in cellular research.
m-PEG24-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide functional group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. Its unique reactivity enables the efficient conjugation of various biomolecules, facilitating the development of targeted degradation strategies in cellular research.
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