m-PEG4-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide functional group, it is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. This reagent is valuable for enhancing target specificity and efficacy in pharmacological research applications.
m-PEG4-azide is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an azide functional group, it is capable of participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules. This reagent is valuable for enhancing target specificity and efficacy in pharmacological research applications.
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