Fig. 1 · Structure
Documents & Downloads
m-PEG7-azide
PROTAC Linker
m-PEG7-azide serves as a versatile PEG-based linker for the synthesis of PROTACs, functioning through its azide group. This reagent is effective in click chemistry, specifically participating in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can facilitate strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) functionalized compounds. This makes m-PEG7-azide a valuable tool for advancing targeted protein degradation research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 208987-04-6 |
| Applications | PROTAC Linker |
| Formula | C15H31N3O7 |
| Molecular Weight | 365.42 |
| SMILES | COCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.