m-PEG8-(CH2)12-phosphonic acid ethyl ester serves as a PEG-based linker for PROTAC synthesis, facilitating the design of bifunctional molecules that target and degrade specific proteins via the ubiquitin-proteasome system. Its structural attributes enhance solubility and bioavailability, making it suitable for application in various drug discovery and developmental research. This linker allows researchers to explore targeted protein degradation as a therapeutic strategy, thus advancing the field of targeted therapies and precision medicine.
m-PEG8-(CH2)12-phosphonic acid ethyl ester serves as a PEG-based linker for PROTAC synthesis, facilitating the design of bifunctional molecules that target and degrade specific proteins via the ubiquitin-proteasome system. Its structural attributes enhance solubility and bioavailability, making it suitable for application in various drug discovery and developmental research. This linker allows researchers to explore targeted protein degradation as a therapeutic strategy, thus advancing the field of targeted therapies and precision medicine.
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