M8-B (hydrochloride)

Catalog No.: A22607
TRPM8 antagonist
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).
Grouped product items
Product Name Price Stock Qty
M8-B (hydrochloride) 1mg
$23.00
In stock
M8-B (hydrochloride) 2mg
$39.00
In stock
M8-B (hydrochloride) 5mg
$75.00
In stock
M8-B (hydrochloride) 10mg
$120.00
In stock
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Biological Activity
Discription M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).
Product Information
Catalog Num A22607
Formula C22H24N2O3S.HCl
Molecular Weight 433
CAS Number 883976-12-3
SMILES COC(C=C(CN(C(C1=CC=CS1)=O)CCN)C=C2)=C2OCC3=CC=CC=C3.Cl
Synonyms M8B (hydrochloride),M8 B (hydrochloride)
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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