Macozinone

Catalog No.: A21488
DprE inhibitor

Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2'-oxidase) inhibitor.

Grouped product items
Product Name Price Stock Qty
Macozinone 5mg
$130.00
In stock
Macozinone 10mg
$223.00
In stock
Macozinone 50mg
$662.00
In stock
Macozinone 100mg
$1,325.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Macozinone has been cited by 1 publications
  • Thanh Quang Nguyen, .et al. , Antimicrob Agents Chemother, 2022, Dec 20;66(12):e0044822 PMID: 36321819
  • Biological Activity
    Discription

    Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2'-oxidase) inhibitor.

    Product Information
    Catalog Num A21488
    Formula C20H23F3N4O3S
    Molecular Weight 456.48
    CAS Number 1377239-83-2
    SMILES O=C1C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2SC(N3CCN(CC4CCCCC4)CC3)=N1
    Synonyms PBTZ169, PBTZ 169, PBTZ-169
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 5 mg/mL (10.95 mM)
    Water Insoluble
    Ethanol 4 mg/mL (8.76 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.91 mL 109.53 mL 219.07 mL
    0.5 mM 4.38 mL 21.91 mL 43.81 mL
    1 mM 2.19 mL 10.95 mL 21.91 mL
    5 mM 0.44 mL 2.19 mL 4.38 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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