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Mal-amido-PEG24-TFP ester

Catalog No.: A83816
PROTAC Linkers
Mal-amido-PEG24-TFP ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound enhances the solubility and stability of PROTACs, facilitating targeted protein degradation in cellular models. Its versatility makes it suitable for various applications in drug discovery and development, particularly in exploring novel therapeutic strategies for modulating protein levels within cells.
Mal-amido-PEG24-TFP ester 2384191-62-0 PROTAC Linkers
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-amido-PEG24-TFP ester is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis targeting chimeras). This compound enhances the solubility and stability of PROTACs, facilitating targeted protein degradation in cellular models. Its versatility makes it suitable for various applications in drug discovery and development, particularly in exploring novel therapeutic strategies for modulating protein levels within cells.
Product Information
Catalog NumA83816
FormulaC64H108F4N2O29
Molecular Weight1445.53
CAS Number2384191-62-0
SMILESO=C(CCN1C(C=CC1=O)=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC2=C(F)C(F)=CC(F)=C2F)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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