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Mal-amido-PEG9-NH-Boc

Catalog No.: A83157
PROTAC Linkers
Mal-amido-PEG9-NH-Boc is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins for selective degradation via the ubiquitin-proteasome system. It is suitable for applications in drug development and targeted protein degradation research, providing enhanced solubility and stability in biological assays.
Mal-amido-PEG9-NH-Boc 2182602-20-4 PROTAC Linkers
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-amido-PEG9-NH-Boc is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins for selective degradation via the ubiquitin-proteasome system. It is suitable for applications in drug development and targeted protein degradation research, providing enhanced solubility and stability in biological assays.
Product Information
Catalog NumA83157
FormulaC32H57N3O14
Molecular Weight707.81
CAS Number2182602-20-4
SMILESO=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O
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