Mal-PEG2-NH2 serves as a polyethylene glycol (PEG)-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of PROTACs by linking E3 ligases to target proteins, promoting targeted degradation. Its use is critical in drug discovery, advancing the development of therapeutic agents that can selectively eliminate specific proteins within biological systems.
Mal-PEG2-NH2 serves as a polyethylene glycol (PEG)-based linker for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of PROTACs by linking E3 ligases to target proteins, promoting targeted degradation. Its use is critical in drug discovery, advancing the development of therapeutic agents that can selectively eliminate specific proteins within biological systems.
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