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Mal-PFP ester

Catalog No.: A82772
PROTAC Linker
Mal-PFP ester is a strategically designed PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It features an alkyl/ether backbone that enhances the linkage between the warhead and E3 ligase, promoting targeted protein degradation. This compound is essential for researchers looking to develop novel PROTACs for therapeutic applications in cancer and other diseases.
Mal-PFP ester 138194-55-5 PROTAC Linker
Grouped product items
Size Price Stock Qty
25mg
$40.00
In stock
50mg
$65.00
In stock
100mg
$105.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PFP ester is a strategically designed PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It features an alkyl/ether backbone that enhances the linkage between the warhead and E3 ligase, promoting targeted protein degradation. This compound is essential for researchers looking to develop novel PROTACs for therapeutic applications in cancer and other diseases.
Product Information
Catalog NumA82772
FormulaC13H6F5NO4
Molecular Weight335.18
CAS Number138194-55-5
SMILESFC1=C(F)C(F)=C(F)C(F)=C1OC(CCN2C(C=CC2=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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PROTAC > PROTAC Linker