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Manidipine 2HCl

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Catalog No. A10554

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Manidipine dihydrochloride 50mg A10554-50

Regular Price: $40.00

Special Price: $36.00

Manidipine dihydrochloride 100mg A10554-100

Regular Price: $70.00

Special Price: $63.00

Manidipine dihydrochloride 200mg A10554-200

Regular Price: $120.00

Special Price: $108.00

Manidipine dihydrochloride 10mM * 1mL in DMSO A10554-10mM-D

Regular Price: $64.00

Special Price: $57.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Manidipine 2HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.

Manidipine 2HCl

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Publications citing Adooq Products
Manidipine 2HCl Citations (1)
  • Noriaki Ikemura,, .et al. Inhibitory effects of antihypertensive drugs on human cytochrome P450 2J2 activity: Potent inhibition by azelnidipine and manidipine, Chem -Biol Interact, 2019, 306:1-9

Chemical Information

Catalog Num A10554
Actions N/A
M. Wt 683.6
Formula C35H40Cl2N4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 89226-75-5
Synonyms CV-4093
SMILES CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC.Cl.Cl

Biological Activity

Description
Manidipine 2HCl is a HCl salt form of Manidipine which is a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM.
Targets
Calcium channel
2.6 nM

Solubility

Solubility (25°C)* In vitro DMSO 21 mg/mL (30.71 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.63 mL 73.14 mL 146.28mL
0.5 mM 2.93 mL 14.63 mL 29.26 mL
1 mM 1.46 mL 7.31 mL 14.63 mL
5 mM 0.29 mL 1.46 mL 2.93 mL

*The above data is based on the productmolecular weight 683.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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