MAP855

Name: MAP855
Brand: Adooq Bioscience
SKU: A24202
Rating: 5 (288 reviews)

Catalog No.: A24202

MEK1/2 inhibitor

MAP855 is a highly potent, selective, ATP-competitive, and orally active MEK1/2 kinase inhibitor, with an IC50 of 3 nM for the MEK1–ERK2 cascade and a pERK EC50 of 5 nM. It exhibits equipotent inhibitory activity against both wild-type and mutant forms of MEK1/2, making it a valuable tool for MAPK pathway research.

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Grouped product items
Size	Price	Stock
5mg	$675.00	In stock
10mg	$1,163.00	In stock
50mg	$3,450.00	In stock
100mg	$6,750.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	MAP855 is a highly potent, selective, ATP-competitive, and orally active MEK1/2 kinase inhibitor, with an IC50 of 3 nM for the MEK1–ERK2 cascade and a pERK EC50 of 5 nM. It exhibits equipotent inhibitory activity against both wild-type and mutant forms of MEK1/2, making it a valuable tool for MAPK pathway research.

Product Information

Catalog Num	A24202
Formula	C28H23ClF2N6O3
Molecular Weight	564.97
CAS Number	1660107-77-6
SMILES	CC1=NC2=C(C3=CC(C4=C(C=C(C=C4)OC5=NC=CC=N5)Cl)=C(F)C=C3N=C2)N1[C@]6([H])[C@H](CN(CC6)C(CO)=O)F
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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