Maraviroc (UK-427857)
Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's Maraviroc (UK-427857) has been cited by 3 publications
- Roman V Uzhachenko, .et al. , Cell Rep, 2021, Apr 6;35(1):108944 PMID: 33826903
- Karampoor S, .et al. , Int Immunopharmacol, 2020, Mar;80:106138 PMID: 32007705
- Taisuke Ito, .et al. , JCIA, 2020, 22 January
Biological Activity
| Description | Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A10556 |
|---|---|
| Formula | C29H41F2N5O |
| Molecular Weight | 513.7 |
| CAS Number | 376348-65-1 |
| SMILES | CC1=NN=C(N1C2C[C@H]3CC[C@@H](C2)N3CC[C@@H](C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C |
| Synonyms | Celsentri |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 91 mg/mL (177.15 mM) | |
| Water | Insoluble | ||
| Ethanol | 91 mg/mL (177.15 mM) | ||
| In vivo | 2% DMSO+corn oil | 9 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.47 mL | 97.33 mL | 194.67 mL |
| 0.5 mM | 3.89 mL | 19.47 mL | 38.93 mL |
| 1 mM | 1.95 mL | 9.73 mL | 19.47 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.89 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
