Maraviroc (UK-427857)

Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.
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Maraviroc 5mg
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Maraviroc 25mg
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Maraviroc 50mg
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Maraviroc 100mg
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Maraviroc (UK-427857) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's Maraviroc (UK-427857) has been cited by 3 publications
  • Roman V Uzhachenko, .et al. , Cell Rep, 2021, Apr 6;35(1):108944 PMID: 33826903
  • Karampoor S, .et al. , Int Immunopharmacol, 2020, Mar;80:106138 PMID: 32007705
  • Taisuke Ito, .et al. , JCIA, 2020, 22 January
  • Biological Activity
    Discription Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.
    Target Value
    Product Information
    Catalog Num A10556
    Formula C29H41F2N5O
    Molecular Weight 513.7
    CAS Number 376348-65-1
    SMILES CC1=NN=C(N1C2C[C@H]3CC[C@@H](C2)N3CC[C@@H](C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C
    Synonyms Celsentri

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 91 mg/mL (177.15 mM)
    Water Insoluble
    Ethanol 91 mg/mL (177.15 mM)
    In vivo 2% DMSO+corn oil 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.47 mL 97.33 mL 194.67 mL
    0.5 mM 3.89 mL 19.47 mL 38.93 mL
    1 mM 1.95 mL 9.73 mL 19.47 mL
    5 mM 0.39 mL 1.95 mL 3.89 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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