Mardepodect hydrochloride is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 value of 0.37 nM and demonstrating greater than 1000-fold selectivity over other phosphodiesterases. This compound has the ability to cross the blood-brain barrier, making it a valuable tool in neurological research. Its selective inhibition of PDE10A may provide insights into disorders such as schizophrenia and movement disorders, offering potential pathways for therapeutic development.
Mardepodect hydrochloride is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), exhibiting an IC50 value of 0.37 nM and demonstrating greater than 1000-fold selectivity over other phosphodiesterases. This compound has the ability to cross the blood-brain barrier, making it a valuable tool in neurological research. Its selective inhibition of PDE10A may provide insights into disorders such as schizophrenia and movement disorders, offering potential pathways for therapeutic development.
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