Marimastat

Catalog No.: A12826

MMP inhibitor

Marimastat

Marimastat Chemical Structure

CAS NO. 154039-60-8

Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$110.00
25 mg
$210.00
50 mg
$330.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Lv Y, .et al. Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells, ACS Nano, 2018, Feb 27;12(2):1519-1536 PMID: 29350904
  • ChaoQin, .et al. Matrix metalloproteinases sensitive multifunctional micelles for inhibition of metastatic tumor growth and metastasis, Powder Technol, 2018, In Press

Biological Activity

Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.
Targets
Target Value
MMP-9IC50: 3nM
MMP-1IC50: 5nM
MMP-2IC50: 6nM
MMP-14IC50: 9nM
MMP-7IC50: 16nM
MMP-3IC50: 230nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.17 mL 150.87 mL 301.74 mL
0.5 mM 6.03 mL 30.17 mL 60.35 mL
1 mM 3.02 mL 15.09 mL 30.17 mL
5 mM 0.6 mL 3.02 mL 6.03 mL

*The above data is based on the productmolecular weight 331.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12826
Actions Inhibitor
M. Wt 331.41
Formula C15H29N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 154039-60-8
SMILES CC(C)C[[email protected]]([[email protected]@H](C(=O)NO)O)C(=O)N[[email protected]](C(=O)NC)C(C)(C)C

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