MC3343 is a DNMT inhibitor (EC50: 5.7 μM) and potent DNA binder that inhibits tumor proliferation by arresting osteosarcoma (OS) cells in the G1 or G2/M phases. It promotes osteoblastic differentiation by specifically reactivating genes involved in this physiological process.
MC3343 is a DNMT inhibitor (EC50: 5.7 μM) and potent DNA binder that inhibits tumor proliferation by arresting osteosarcoma (OS) cells in the G1 or G2/M phases. It promotes osteoblastic differentiation by specifically reactivating genes involved in this physiological process.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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