Mdivi-1

Catalog No.: A14316

DRP1 inhibitor

Mdivi-1

Mdivi-1 Chemical Structure

CAS NO. 338967-87-6

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $90.00

Special Price $81.00

50 mg

Regular Price: $160.00

Special Price $144.00

100 mg

Regular Price: $280.00

Special Price $252.00

10mM * 1mL in DMSO

Regular Price: $80.00

Special Price $72.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.
Targets
Dynamin1
1 μM-10 μM
In vitro DMSO 70 mg/mL (198.17 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.31 mL 141.55 mL 283.11 mL
0.5 mM 5.66 mL 28.31 mL 56.62 mL
1 mM 2.83 mL 14.16 mL 28.31 mL
5 mM 0.57 mL 2.83 mL 5.66 mL

*The above data is based on the productmolecular weight 353.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A14316
Actions Inhibitor
M. Wt 353.22
Formula C15H10Cl2N2O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 338967-87-6
Synonyms Mdivi 1, Mdivi1
SMILES COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl

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