Mdivi-1

Catalog No.: A14316
DRP1 inhibitor
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.
Grouped product items
Product Name Price Stock Qty
Mdivi-1 25mg
$90.00
In stock
Mdivi-1 50mg
$160.00
In stock
Mdivi-1 100mg
$280.00
In stock
Mdivi-1 10mM * 1mL in DMSO
$80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Mdivi-1 has been cited by 2 publications
  • Umut Kerem Kolac, .et al. , Mol Biol Rep, 2023, Jan;50(1):493-506 PMID: 36352179
  • KOLAC UK, .et al. , Research Square, 2022, 03 Jun
  • Biological Activity
    Discription Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 uM.
    Targets
    Target Value
    Product Information
    Catalog Num A14316
    Formula C15H10Cl2N2O2S
    Molecular Weight 353.22
    CAS Number 338967-87-6
    SMILES COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl
    Synonyms Mdivi 1, Mdivi1
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 62 mg/mL (175.52 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5% DMSO+40% PEG 300+5% Tween 80+ddH2O 6 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.31 mL 141.55 mL 283.11 mL
    0.5 mM 5.66 mL 28.31 mL 56.62 mL
    1 mM 2.83 mL 14.16 mL 28.31 mL
    5 mM 0.57 mL 2.83 mL 5.66 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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