MDL 28170

Catalog No.: A15303
Calpain Inhibitor III
MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.
Grouped product items
Product Name Price Stock Qty
MDL 28170 10mg
$45.00
In stock
MDL 28170 25mg
$100.00
In stock
MDL 28170 50mg
$190.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's MDL 28170 has been cited by 1 publications
  • Barker BS, .et al. , Neuroscience, 2019, Nov 26. pii: S0306-4522(19)30796-1 PMID: 31783100
  • Biological Activity
    Discription MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.
    Product Information
    Catalog Num A15303
    Formula C22H26N2O4
    Molecular Weight 382.45
    CAS Number 88191-84-8
    SMILES CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2
    Synonyms Calpain Inhibitor III
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 69 mg/mL (180.41 mM)
    Water Insoluble
    Ethanol 9 mg/mL (23.53 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 26.15 mL 130.74 mL 261.47 mL
    0.5 mM 5.23 mL 26.15 mL 52.29 mL
    1 mM 2.61 mL 13.07 mL 26.15 mL
    5 mM 0.52 mL 2.61 mL 5.23 mL
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