MDL 28170

Catalog No.: A15303

Calpain Inhibitor III

MDL 28170

MDL 28170 Chemical Structure

CAS NO. 88191-84-8

MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.

Availability: In stock

Package Price Qty
10 mg
$45.00
25 mg
$100.00
50 mg
$190.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Barker BS, .et al. Screening for Efficacious Anticonvulsants and Neuroprotectants in Delayed Treatment Models of Organophosphate-induced Status Epilepticus, Neuroscience, 2019, Nov 26. pii: S0306-4522(19)30796-1 PMID: 31783100

Biological Activity

MDL 28170 is a cell permeable selective inhibitor of Calpain 1, a Ca2+-dependent cysteine protease which has been implicated in apoptosis of immune cells as well as neuronal cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.74 mL 261.47 mL
0.5 mM 5.23 mL 26.15 mL 52.29 mL
1 mM 2.61 mL 13.07 mL 26.15 mL
5 mM 0.52 mL 2.61 mL 5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15303
Actions Inhibitor
M. Wt 382.45
Formula C22H26N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 88191-84-8
Synonyms Calpain Inhibitor III
SMILES CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2

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