Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2

Catalog No.: A42956
Cleavable ADC Linker
Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents upon internalization by target cells, enhancing the therapeutic efficacy and reducing off-target effects. Its application in ADC development supports the advancement of targeted cancer therapies and other biopharmaceutical innovations.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
50mg
$60.00
In stock
100mg
$90.00
In stock
250mg
$185.00
In stock
500mg
$305.00
In stock
1g
$505.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMe-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable linker specifically designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents upon internalization by target cells, enhancing the therapeutic efficacy and reducing off-target effects. Its application in ADC development supports the advancement of targeted cancer therapies and other biopharmaceutical innovations.
Product Information
Catalog NumA42956
FormulaC20H21NO13
Molecular Weight483.38
CAS Number148579-93-5
SMILESO=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(C=O)C=C2[N+]([O-])=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
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