Fig. 1 · Structure
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Methyl 4-hydroxybicyclo2.2.2octane-1-carboxylate
PROTAC Linker
Methyl 4-hydroxybicyclo[2.2.2]octane-1-carboxylate is a PROTAC linker designed to facilitate the development of Proteolysis Targeting Chimeras (PROTACs). This compound enables selective degradation of target proteins through targeted ubiquitination, playing a crucial role in modulating cellular pathways. Its application in PROTAC synthesis allows researchers to explore innovative therapeutic strategies in cancer and various diseases by harnessing the power of targeted protein degradation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23062-53-5 |
| Applications | PROTAC Linker |
| Formula | C10H16O3 |
| Molecular Weight | 184.24 |
| SMILES | O=C(OC)C12CCC(O)(CC1)CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.