Methyl-PEG4-acyl chloride

Catalog No.: A83035
PROTAC Linkers
Methyl-PEG4-acyl chloride is a PEG-derived compound that serves as an effective linker for PROTAC (proteolysis-targeting chimera) synthesis. Its primary mechanism involves facilitating the assembly of bifunctional molecules designed to induce targeted protein degradation. This reagent is essential for researchers developing PROTACs to explore the modulation of protein function and cellular pathways in various biological contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMethyl-PEG4-acyl chloride is a PEG-derived compound that serves as an effective linker for PROTAC (proteolysis-targeting chimera) synthesis. Its primary mechanism involves facilitating the assembly of bifunctional molecules designed to induce targeted protein degradation. This reagent is essential for researchers developing PROTACs to explore the modulation of protein function and cellular pathways in various biological contexts.
Product Information
Catalog NumA83035
FormulaC10H19ClO6
Molecular Weight270.71
CAS Number62124-69-0
SMILESCOCCOCCOCCOCCOC(Cl)=O
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