Metopimazine-d6 is a deuterium-labeled derivative of Metopimazine, a phenothiazine compound that functions primarily as a selective antagonist of dopamine D2 receptors. It is characterized by its inability to penetrate the blood-brain barrier, making it effective in inhibiting dopamine activity in peripheral regions and the chemoreceptor trigger zone, thus reducing nausea and vomiting. Metopimazine is commonly utilized in the management of chemotherapy-induced nausea and vomiting, with minimal central nervous system effects owing to its limited brain access. This stable isotope compound is valuable for research applications involving pharmacokinetics and metabolic studies.
Metopimazine-d6 is a deuterium-labeled derivative of Metopimazine, a phenothiazine compound that functions primarily as a selective antagonist of dopamine D2 receptors. It is characterized by its inability to penetrate the blood-brain barrier, making it effective in inhibiting dopamine activity in peripheral regions and the chemoreceptor trigger zone, thus reducing nausea and vomiting. Metopimazine is commonly utilized in the management of chemotherapy-induced nausea and vomiting, with minimal central nervous system effects owing to its limited brain access. This stable isotope compound is valuable for research applications involving pharmacokinetics and metabolic studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
