Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Macquarimicin A is a potent antibiotic known for its ability to inhibit bacterial growth. It demonstrates significant antimicrobial activity against a range of gram-positive and some gram-negative bacteria. This compound is primarily utilized in microbiological research to study antibiotic resistance mechanisms and the effects of antibiotic treatment. Its unique structure and mode of action make Macquarimicin A an important tool for exploring and developing new therapeutic strategies in infectious disease research. -
Antibiotic
Pristinamycin IIC is an ester peptide antibiotic targeting Gram-positive bacteria. It exhibits potent antibacterial activity against a range of pathogenic strains, making it valuable in studies related to antibiotic resistance and bacterial infections. Research applications include in vitro susceptibility testing and the evaluation of antibiotic efficacy in various clinical scenarios. -
Angucycline Antibiotic
Saquayamycin B is an angucycline antibiotic known for its potent antitumor activity. It exhibits significant inhibition against human lung (H-460) and breast cancer (MCF-7) cell lines, demonstrating GI50 values of 12.2 µM and 15.2 µM, respectively. This compound is a valuable tool for research in cancer therapeutics and antibiotic development. -
Antibiotic
Phleomycin G is a heteropeptide antibiotic that primarily targets bacterial ribosomes. It exhibits potent activity against Gram-positive and some Gram-negative bacteria, as well as mycobacteria. Research indicates that Phleomycin G can prolong the survival of mice with Ehrman's ascites carcinoma and has demonstrated inhibitory effects on various carcinoma types in murine models. This compound is valuable for studies involving bacterial infections and cancer therapeutics. -
Antibiotic
Pluracidomycin A1 is a carbapenem antibiotic that targets bacterial cell wall synthesis. It exhibits potent activity against both Gram-positive and Gram-negative bacteria while effectively inhibiting β-lactamase enzymes. This makes it a valuable reagent for research focused on antibiotic resistance and the mechanisms of bacterial pathogenicity. -
Macrolide Antibiotic
YM 133 is a semisynthetic macrolide antibiotic that exerts potent bactericidal activity. It demonstrates effectiveness against Erythromycin, Josamycin, and Rokitamycin-resistant strains of staphylococci, streptococci, Bacteroides spp., and Clostridium spp., showcasing strong activity against macrolide-resistant bacteria and anaerobic pathogens. This compound is valuable for antibacterial research focusing on resistant infections and macrolide antibiotic efficacy. -
Antibiotic
Arylomycin B1 is a lipohexapeptide antibiotic targeting Gram-positive bacteria through inhibition of bacterial signal peptidase. It exhibits potent antibacterial activity and serves as a valuable research tool for studying bacterial resistance mechanisms and the development of novel antibiotic therapies. This compound is essential for investigations in microbiology and antibiotic efficacy. -
Antibiotic
Nafithromycin is an orally available antibiotic that primarily targets bacterial pathogens, effectively inhibiting strains responsible for community-acquired pneumonia, including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and methicillin-susceptible Staphylococcus aureus. This compound exhibits a minimum inhibitory concentration (MIC90) of 0.12 mg/liter against macrolide-resistant and telithromycin-insensitive strains of Streptococcus pneumoniae. Nafithromycin is useful in research applications focused on antibiotic resistance and the treatment of respiratory infections. -
Antitumor Antibiotic
Hydroxymycotrienin B is an Ansa antibiotic with potent antitumor activity. It effectively inhibits the proliferation of human neck tumor cell lines, demonstrating a stronger inhibitory effect on HPV gene positive cells, such as HeLa, CaSKi, and SiHa, compared to HPV gene negative cells. This compound is of significant interest in cancer research and the development of targeted therapies against HPV-associated malignancies. -
Antibiotic
Griseusin A is a quinone-based antibiotic that primarily targets Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool in the study of bacterial infections and resistance mechanisms. Griseusin A's unique mechanism may provide insights into novel therapeutic approaches for treating Gram-positive bacterial infections. -
Antibiotic
Rifamexil is an antibiotic derivative of Rifamycin, specifically designed to inhibit bacterial RNA polymerase. It demonstrates effective activity against Mycobacterium avium complex and various other mycobacterial strains. This reagent is valuable for research applications focused on antimicrobial resistance and the development of treatments for mycobacterial infections. -
Antibiotic
Y-05460M-A is a substituted isocoumarin antibiotic that demonstrates inhibitory activity against both Gram-positive and Gram-negative bacterial strains. Additionally, Y-05460M-A exhibits cytotoxic effects against P388 lymphatic leukemia cells and has been shown to possess antiulcer activity. This compound is a one-carbon lower homologue of PM-04128 and can be synthesized from N-Boc-L-valine, making it a valuable reagent for antimicrobial and anticancer research. -
Antibiotic
Napyradiomycin C2 is an antibiotic that primarily targets Gram-positive bacteria and mycobacteria. It exhibits significant antibacterial activity, making it a valuable compound for research focused on bacterial infections and resistance mechanisms. Its unique structure and mode of action can facilitate studies in drug development and microbiology. -
Antibiotic
Rac N-Demethyl promethazine hydrochloride is a metabolite of Phenothiazine, targeting various biological pathways. This compound exhibits antibiotic properties, demonstrating insecticidal, fungicidal, antibacterial, and anthelmintic activities. It is utilized in research applications focused on understanding mechanisms of action in microbial resistance and therapeutic efficacy. -
Antibiotic
44-Homooligomycin B is an antitumor antibiotic that primarily targets fungal infections. It exhibits potent activity against fungal strains, including Aspergillus, Penicillium, and Fusarium, while lacking effectiveness against yeast and bacteria. Additionally, 44-Homooligomycin B demonstrates moderate antitumor activity in vivo against Colon 26 cancer models, making it a valuable compound for research in oncology and mycology. -
Beta-lactam Antibiotic
RU44790 is a monocyclic beta-lactam antibiotic that demonstrates potent efficacy against gram-negative bacteria and exhibits remarkable resistance to hydrolysis by various beta-lactamases. This compound serves as a valuable tool in antibacterial research, facilitating investigations into bacterial resistance mechanisms and the development of novel therapeutic strategies. -
Antibiotic
Coumamidine γ2 is an alkaline sugar antibiotic known for its broad-spectrum antibacterial activity, particularly against Pseudomonas aeruginosa. This compound demonstrates efficacy in inhibiting bacterial growth and is valuable for research applications involving antibiotic resistance and infection models. Its unique mechanism offers insights into microbial interactions and potential therapeutic approaches in clinical settings. -
Antibiotic
Valanimycin is an antibiotic that targets Escherichia coli by interacting with DNA, effectively inhibiting bacterial growth. In addition to its antibacterial properties, Valanimycin demonstrates cytotoxic effects against mouse leukemia cell lines, including L1210, P388/S, and P388/ADR, with IC50 values of 0.79, 2.65, and 1.44 μg/mL, respectively. It also exhibits significant antitumor efficacy in models of ehrlich ascites tumors and L1210 cells in mice, making it a valuable compound for cancer research and antibiotic studies. -
Antibiotic
Napyradiomycin B1 is an antibiotic that exhibits potent activity against Gram-positive bacteria and mycobacteria. It demonstrates minimal effectiveness against Gram-negative bacteria and fungi. The compound has an IC50 of 2.2 μg/mL in leukemia L-1210 cell lines, highlighting its potential for research in cancer and infectious disease studies. -
Antibiotic
Nikkomycin Lx is an antibiotic derived from Streptomyces tendae TU901, targeting the inhibition of fungal cell wall synthesis. It exhibits significant anti-Candida albicans activity, making it valuable for studies focused on fungal infections and resistance mechanisms. This reagent is suitable for research applications involving antifungal efficacy and related therapeutic investigations. -
Antibiotic
Maridomycin IV is a macrolide antibiotic that targets Gram-positive bacteria and mycoplasma. Demonstrating potent antibacterial activity, it effectively protects mice from Gram-positive bacterial infections. This compound is useful in research applications focused on evaluating antibiotic efficacy and understanding bacterial resistance mechanisms. -
Antibiotic
Cytorhodin X is a cytotoxic antibiotic that targets bacterial and cancer cell proliferation. It effectively inhibits the growth of L1210 murine leukemia cells, demonstrating an ED50 value of 0.36 μM. This compound is valuable for research applications involving cancer treatment and antibiotic efficacy studies. -
Antibiotic
Micacocidin C is an antibiotic derived from Pseudomonas sp. No. 57, primarily targeting Mycoplasma species. It demonstrates potent antibacterial activity, making it valuable for research applications focused on combating mycoplasmal infections and understanding antibiotic resistance mechanisms. -
Antitumor Antibiotic
Baumycin A1 is an antitumor antibiotic that primarily exerts its effects through the inhibition of DNA synthesis. It demonstrates significant cytotoxic activity against various cancer cell lines, making it a valuable tool for cancer research. Researchers can utilize Baumycin A1 to explore mechanisms of tumorigenesis and to develop novel therapeutic strategies in oncology. -
Antibiotic
Sannamycin F is an aminoglycoside antibiotic that primarily targets bacterial protein synthesis. It exhibits weak antibacterial activity against both Gram-positive and Gram-negative bacteria. This compound is suitable for studies focusing on antibiotic resistance mechanisms and the development of new antimicrobial agents. -
Antibiotic
Platenomycin C3 is a macrolide antibiotic that targets Gram-positive bacteria through inhibition of bacterial fatty acid synthesis. Exhibiting potent antimicrobial activity, it is particularly effective against various strains of resistant pathogens. This compound serves as a valuable research tool for studies focused on antibiotic resistance and bacterial metabolism. -
Antitumor Antibiotic
1-Hydroxysulfurmycin A is an anthracycline antibiotic that exerts its primary activity through the intercalation of DNA, disrupting replication and transcription processes. This compound demonstrates significant antitumor properties and exhibits activity against Gram-positive bacteria. It is primarily utilized in cancer research and studies focused on bacterial resistance mechanisms. -
Antibiotic
Pyrrolosporin A is an antibiotic that exhibits activity against Gram-negative bacteria. It demonstrates weak bactericidal properties, making it of interest in studies focused on antibiotic resistance and the mechanisms of bacterial infection. This compound can serve as a valuable tool in research aimed at developing new antimicrobial therapies. -
Antibiotic
Mureidomycin A is an antibiotic that exhibits potent activity against Pseudomonas aeruginosa. This compound inhibits bacterial protein synthesis, making it a valuable tool in studying bacterial resistance and developing new therapeutic strategies. Its specific targeting of pathogenic bacteria supports research in infectious disease and antibiotic development. -
Antibiotic
Neutramycin is a neutral macrolide antibiotic that targets bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits broad-spectrum antimicrobial activity, making it effective against a variety of Gram-positive and Gram-negative bacteria. This compound is utilized in research applications focused on antibiotic resistance, mechanisms of action in microbial physiology, and the development of new therapeutic strategies. -
Antibiotic
Promothiocin B is an antibiotic that primarily targets bacterial cell wall synthesis. It exhibits potent antibacterial activity with a minimum induction concentration of 0.1 μg/mL for the tipA promoter. This compound is valuable for research applications involving the study of antibiotic mechanisms and resistance, as well as in the development of novel therapeutic strategies against bacterial infections. -
Antibiotic
Griseoviridin is an Estopeptide antibiotic that primarily targets bacterial cell wall synthesis. This compound exhibits potent activity against Gram-positive bacteria and demonstrates selective effects on certain Gram-negative bacteria. It is useful in research applications involving antimicrobial susceptibility testing and the study of antibiotic resistance mechanisms. -
Antibiotic
Pyrisulfoxin B is an antibiotic derived from the bacterium Streptomyces callfornicus BS-75. It exhibits significant antibacterial activity, making it suitable for research focused on antimicrobial agents and their mechanisms of action. Pyrisulfoxin B can be utilized in studies investigating antibiotic resistance and developing novel therapeutic strategies. -
Antibiotic
Tetromycin C5 is a broad-spectrum antibiotic targeting gram-positive bacteria, including strains that exhibit drug resistance. It demonstrates significant antibacterial activity, making it a valuable tool for research in infectious disease and antibiotic resistance studies. This compound is ideal for exploring mechanisms of antimicrobial action and developing novel therapeutic strategies. -
Antibiotic
Collinone is a recombinant angular polyketide antibiotic that exhibits antibacterial activity primarily against gram-positive bacteria. In addition to its antimicrobial properties, Collinone demonstrates cytotoxic effects, making it a valuable compound for research in microbial resistance and bioactivity studies. Its unique structure and mechanism of action provide insights into antibiotic development and potential therapeutic applications. -
Antibiotic
Polymyxin T1 is an antibiotic derived from Bacillus polymyxa E-12, primarily targeting Gram-negative bacteria. It exhibits bactericidal activity by disrupting the bacterial cell membrane, leading to cell lysis. Due to its specific action, Polymyxin T1 is valuable for research in studying bacterial resistance and exploring new antimicrobial strategies. -
Antibiotic
Seldomycin factor 3 is an aminoglycoside antibiotic that exhibits a broad spectrum of antimicrobial activity. It is primarily used in research applications to investigate mechanisms of bacterial resistance and to study antibiotic efficacy against various microbial strains. This compound serves as a valuable tool in the development of new therapeutic strategies to combat infectious diseases. -
Antitumor Antibiotic
Fluopsin F is an antitumor antibiotic that demonstrates significant antibacterial properties against both Gram-positive and Gram-negative bacteria. Its unique composition containing metallic iron contributes to its efficacy in targeting and inhibiting tumor growth. Fluopsin F is suitable for research applications focused on cancer treatment and antibiotic resistance studies. -
Antibiotic Agent
Hormaomycin is a potent and selective macrocyclic antibiotic agent that targets bacterial cell membranes. It exhibits broad-spectrum antibiotic activity against various Gram-positive bacteria. This compound is valuable for research applications focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Antibiotic
3-Hydroxyrifamycin S is an Ansamycin antibiotic that targets bacterial ribosomes to inhibit protein synthesis. This compound exhibits significant activity against Gram-positive bacteria while demonstrating weaker efficacy against Gram-negative bacteria. It is primarily utilized in research focused on antibiotic resistance and the mechanisms of bacterial infection. -
Aminoglycoside Antibiotic
Gentamicin B is an aminoglycoside antibiotic derived from Micromonospora echinospora. It exhibits potent antibacterial activity against a broad spectrum of Gram-negative bacteria. This compound is primarily utilized in research focusing on its potential for inducing ataxia and evaluating renal toxicity. -
Antibiotic
Amythiamicin D is a thiopeptide antibiotic that primarily targets Gram-positive bacteria, effectively inhibiting their growth. It demonstrates significant antibacterial activity and is utilized in research applications focusing on bacterial resistance mechanisms and the exploration of novel antimicrobial agents. This compound serves as a valuable tool for investigating the pharmacological properties and therapeutic potential of thiopeptide antibiotics. -
Antibiotic
Saroaspidin C is an antibiotic compound derived from Sarothra japonica. It exhibits potent antibacterial activity, making it a valuable tool for research in microbiology and infectious disease studies. This compound can be utilized to investigate mechanisms of action against bacterial pathogens and to explore new therapeutic strategies for treating infections. -
Antitumor Antibiotic
Kapurimycin A1 is an antitumor antibiotic derived from Streptomyces species. It displays potent inhibitory activity against Gram-positive bacteria and exhibits cytotoxic effects on cultured mammalian cells. Additionally, Kapurimycin A1 has demonstrated strong antitumor efficacy against the mouse leukemia P388 cell line, making it a valuable tool for cancer research studies. -
Antibiotic
Napsamycin D is an antibiotic that targets bacterial cell growth. It exhibits strong antibacterial activity specifically against Pseudomonas aeruginosa and other Pseudomonas species, while displaying limited efficacy against other Gram-positive and Gram-negative bacteria. This compound is useful in research settings focused on bacterial infections and antibiotic resistance studies. -
Antibiotic
Macquarimicin B is an antibiotic that primarily targets bacterial RNA synthesis. It exhibits potent antibacterial activity against a range of Gram-positive bacteria, making it valuable in the study of antibiotic resistance and bacterial pathogenesis. This compound is applicable in research focused on the mechanisms of action of antibiotics and the development of novel therapeutic agents for bacterial infections. -
Antibiotic
Atrovenetin is an antibiotic derived from Penicillium species that primarily targets bacterial infections. It demonstrates inhibitory activity against Bacillus subtilis and Staphylococcus aureus, making it relevant for studies on bacterial resistance and antibiotic efficacy. Additionally, Atrovenetin exhibits potent antioxidant properties, contributing to its potential use in research focused on oxidative stress and related biological pathways. -
Antibiotic
Polymyxin A2 is a heteropeptide antibiotic that targets the outer membrane of Gram-negative bacteria, disrupting membrane integrity and leading to cell death. It exhibits stronger antibacterial activity against Gram-negative strains compared to Gram-positive counterparts. Polymyxin A2 is primarily used in microbiological research to study antibiotic resistance mechanisms and to evaluate the efficacy of new antimicrobial agents. -
Antitumor Antibiotic
Baumycin B1 is an antitumor antibiotic that functions by inhibiting DNA synthesis and disrupting cellular replication. This compound exhibits significant cytotoxicity against a variety of cancer cell lines, making it a valuable tool for cancer research. Its mechanism of action offers potential insights into therapeutic strategies for tumor treatment and provides a basis for further investigation into its biological effects. -
Antibiotic
Aspergillic acid is an antibiotic derived from Aspergillus flavus, primarily targeting bacterial pathogens. It exhibits a broad spectrum of antibacterial activity, making it a valuable reagent for microbiological studies. Aspergillic acid is often utilized in research applications focused on antibiotic resistance and the development of new antimicrobial agents.
