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- Viktoria Lazar, .et al. Antibiotic combinations reduce Staphylococcus aureus clearance, Nature, 2022, 610: 540-546 PMID: 36198788
Biological Activity
Minocycline hydrochloride is a broad-spectrum tetracycline antibiotic, acting by binding to the bacterial 30S ribosomal subunit and inhibiting protein synthesis.
| In vitro | DMSO | Insoluble | |
| Water | Warmed: 1 mg/mL (2.02 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.25 mL | 101.23 mL | 202.45 mL |
| 0.5 mM | 4.05 mL | 20.25 mL | 40.49 mL |
| 1 mM | 2.02 mL | 10.12 mL | 20.25 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.05 mL |
*The above data is based on the productmolecular weight 493.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A20954 |
|---|---|
| CAS No. | 13614-98-7 |
| Formula | C23H28ClN3O7 |
| M. Wt | 493.94 |
| Purity | >98% |
| SMILES | OC1=C(C(N)=O)C([C@@]2(O)C(O)=C3C(C4=C(O)C=CC(N(C)C)=C4C[C@@]3([H])C[C@@]2([H])[C@@H]1N(C)C)=O)=O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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