MJ15 is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1), with a Ki of 27.2 pM and an IC50 of 118.9 pM specifically for rat CB1 receptors. This compound has demonstrated significant biological activity in models of obesity and hyperlipidemia, effectively inhibiting food intake and preventing increases in body weight in diet-induced obese rats and mice. MJ15 is valuable for research applications focused on metabolic disorders and the endocannabinoid system.
MJ15 is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1), with a Ki of 27.2 pM and an IC50 of 118.9 pM specifically for rat CB1 receptors. This compound has demonstrated significant biological activity in models of obesity and hyperlipidemia, effectively inhibiting food intake and preventing increases in body weight in diet-induced obese rats and mice. MJ15 is valuable for research applications focused on metabolic disorders and the endocannabinoid system.
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