MK-1775

Catalog No.: A10599
WEE1 Inhibitor
MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.
Grouped product items
Product Name Price Stock Qty
MK-1775 5mg
Special Price $36.00 Regular Price $45.00
In stock
MK-1775 10mg
Special Price $60.00 Regular Price $75.00
In stock
MK-1775 50mg
Special Price $108.00 Regular Price $135.00
In stock
MK-1775 10mM * 1mL in DMSO
Special Price $56.00 Regular Price $70.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's MK-1775 has been cited by 3 publications
  • Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521
  • 2018, .et al. , FEBS Open Bio, 2018, Jun; 8(6): 1001-1012 PMID: 29928579
  • Rulina AV, .et al. , Cell Death Dis, 2016, Dec 1;7(12):e2505 PMID: 27906189
  • Biological Activity
    Discription MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.
    Targets
    Target Value
    Product Information
    Catalog Num A10599
    Formula C27H32N8O2
    Molecular Weight 500.6
    CAS Number 955365-80-7
    SMILES CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
    Synonyms AZD1775
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 71 mg/mL (141.82 mM)
    Water Insoluble
    Ethanol 9 mg/mL (17.97 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.98 mL 99.88 mL 199.76 mL
    0.5 mM 4 mL 19.98 mL 39.95 mL
    1 mM 2 mL 9.99 mL 19.98 mL
    5 mM 0.4 mL 2 mL 4 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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