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Catalog No.: A11135

HIV integrase inhibitor


MK-2048 Chemical Structure

CAS NO. 869901-69-9

MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection.

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Biological Activity

MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection.
In vitro DMSO 9 mg/mL (19.48 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.65 mL 108.25 mL 216.5 mL
0.5 mM 4.33 mL 21.65 mL 43.3 mL
1 mM 2.16 mL 10.82 mL 21.65 mL
5 mM 0.43 mL 2.16 mL 4.33 mL

*The above data is based on the productmolecular weight 461.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11135
Actions Inhibitor
CAS No. 869901-69-9
Formula C21H21ClFN5O4
M. Wt 461.9
Purity >98%
Synonyms MK2048
SMILES CCN1C[[email protected]@H](N2C3=C(C(=C2C1=O)O)C(=O)N(N=C3C(=O)NC)CC4=CC(=C(C=C4)F)Cl)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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