MK-3903

Catalog No.: A17063

AMPK activator

MK-3903

MK-3903 Chemical Structure

CAS NO. 1219737-12-8

MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM). MK-3903 exhibited robust target engagement in mouse liver following oral dosing, leading to improved lipid metabolism and insulin sensitization in mice.

Availability: In stock

Package Price Qty
5 mg
$280.00
10 mg
$480.00
50 mg
$1,400.00
100 mg
$2,000.00
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Biological Activity

MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM). MK-3903 exhibited robust target engagement in mouse liver following oral dosing, leading to improved lipid metabolism and insulin sensitization in mice.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.98 mL 109.91 mL 219.82 mL
0.5 mM 4.4 mL 21.98 mL 43.96 mL
1 mM 2.2 mL 10.99 mL 21.98 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17063
Actions Activator
M. Wt 454.91
Formula C27H19ClN2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1219737-12-8
Synonyms MK3903, MK 3903
SMILES O=C(O)C1=CC(OC2=NC3=CC(C4=CC=C(C5=CC=CC=C5)C=C4)=C(Cl)C=C3N2)=CC=C1C

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