MK-8666 is a potent and selective partial agonist of GPR40, with an EC50 of 0.54 nM for human GPR40. This compound exhibits significant selectivity over other G-protein-coupled receptors, including GPR119, GPR43, GPR41, and GPR120. MK-8666 has demonstrated the ability to lower glucose levels in rodent models, making it a valuable tool in type 2 diabetes research and related metabolic studies.
MK-8666 is a potent and selective partial agonist of GPR40, with an EC50 of 0.54 nM for human GPR40. This compound exhibits significant selectivity over other G-protein-coupled receptors, including GPR119, GPR43, GPR41, and GPR120. MK-8666 has demonstrated the ability to lower glucose levels in rodent models, making it a valuable tool in type 2 diabetes research and related metabolic studies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
