MLN1117 (Serabelisib)

Catalog No.: A15529

p110α inhibitor

MLN1117 (Serabelisib)

MLN1117 (Serabelisib) Chemical Structure

CAS NO. 1268454-23-4

MLN1117, also known as INK1117 and TAK-117, is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity.

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Package Price Qty
10 mg
$120.00
25 mg
$240.00
50 mg
$350.00
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Biological Activity

MLN1117, also known as INK1117 and TAK-117, is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity.
In vitro DMSO 15 mg/mL (41.28 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.54 mL 137.69 mL 275.38 mL
0.5 mM 5.51 mL 27.54 mL 55.08 mL
1 mM 2.75 mL 13.77 mL 27.54 mL
5 mM 0.55 mL 2.75 mL 5.51 mL

*The above data is based on the productmolecular weight 363.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15529
Actions Inhibitor
CAS No. 1268454-23-4
Formula C19H17N5O3
M. Wt 363.13
Solubility DMSO
Purity >98%
Synonyms INK1117, INK-1117, INK 1117, MLN 1117, MLN-1117, TAK-117, TAK 117, TAK117
SMILES O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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