MLN4924 (Pevonedistat)

Name: MLN4924 (Pevonedistat)
SKU: A11260
Price: 72 USD
Rating: 5 (9 reviews)

Catalog No.: A11260

NAE Inhibitor

Adooq's MLN4924 (Pevonedistat) has been cited by 9 publications

NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.

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Grouped product items
Product Name	Price	Stock
MLN4924 5mg	Special Price $72.00 Regular Price $90.00	In stock
MLN4924 10mg	Special Price $112.00 Regular Price $140.00	In stock
MLN4924 25mg	Special Price $224.00 Regular Price $280.00	In stock
MLN4924 50mg	Special Price $360.00 Regular Price $450.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper

Adooq's MLN4924 (Pevonedistat) has been cited by 9 publications

Takumi Ito, .et al. , Research Square, 2023, 2023

Blue-leaf A. Cordes, .et al. , Cancers (Basel), 2023, Mar; 15(6): 1846 PMID: 36980731

Min Dong, .et al. , J Immunother Cancer, 2022, Oct;10(10):e005270 PMID: 36198437

Corentin Mallet, .et al. , J Virol, 2021, Dec 22;JVI0142721 PMID: 34936483

Nobuyuki Shimizu, .et al. , Commun Biol, 2021, Nov 11;4(1):1277 PMID: 34764413

Jalila Chagraoui, .et al. , Cell Stem Cell, 2021, Jan 7;28(1):48-62.e6 PMID: 33417871

Stephan Riesenberg, .et al. , Nat Commun, 2018, 9: 2164 PMID: 29867139

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Richard J. Kraus, .et al. , PLoS Pathog, 2017, Jun; 13(6): e1006404 PMID: 28617871

Biological Activity

Discription	NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.

Product Information

Catalog Num	A11260
Formula	C21H25N5O4S
Molecular Weight	443.5
CAS Number	905579-51-3
SMILES	C1CC2=CC=CC=C2[C@H]1NC3=NC=NC4=C3C=CN4[C@@H]5C[C@H]([C@H](C5)O)COS(=O)(=O)N
Synonyms	MLN-4924
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	78 mg/mL (175.86 mM)
	Water	Insoluble
	Ethanol	78 mg/mL
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.55 mL	112.74 mL	225.48 mL
0.5 mM	4.51 mL	22.55 mL	45.1 mL
1 mM	2.25 mL	11.27 mL	22.55 mL
5 mM	0.45 mL	2.25 mL	4.51 mL

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