Catalog No.
Product Name
Application
Product Information
Product Citation
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NAE Inhibitor
NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival.- Takumi Ito, .et al. , Research Square, 2023, 2023
- Blue-leaf A. Cordes, .et al. , Cancers (Basel), 2023, Mar; 15(6): 1846 PMID: 36980731
- Min Dong, .et al. , J Immunother Cancer, 2022, Oct;10(10):e005270 PMID: 36198437
- Corentin Mallet, .et al. , J Virol, 2021, Dec 22;JVI0142721 PMID: 34936483
- Nobuyuki Shimizu, .et al. , Commun Biol, 2021, Nov 11;4(1):1277 PMID: 34764413
- Jalila Chagraoui, .et al. , Cell Stem Cell, 2021, Jan 7;28(1):48-62.e6 PMID: 33417871
- Stephan Riesenberg, .et al. , Nat Commun, 2018, 9: 2164 PMID: 29867139
- Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
- Richard J. Kraus, .et al. , PLoS Pathog, 2017, Jun; 13(6): e1006404 PMID: 28617871
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NAE Inhibitor
NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. -
NAE inhibitor
TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.