MLN8237 (Alisertib)

On Sale
Catalog No.: A10004
Aurora A Kinase inhibitor
MLN8237 (Alisertib) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Phase 3..
Grouped product items
Product Name Price Stock Qty
MLN8237 5mg
Special Price $42.00 Regular Price $60.00
In stock
MLN8237 10mg
Special Price $70.00 Regular Price $100.00
In stock
MLN8237 50mg
Special Price $185.00 Regular Price $265.00
In stock
MLN8237 200mg
Special Price $535.00 Regular Price $765.00
In stock
MLN8237 (Alisertib) 10mM * 1mL in DMSO
Special Price $56.00 Regular Price $80.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Not your Region? View all Distributors

Adooq Products cited in reputable paper
Adooq's MLN8237 (Alisertib) has been cited by 6 publications
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Bucko PJ, .et al. , Elife, 2019, Dec 24;8. pii: e52220 PMID: 31872801
  • Kimura M, .et al. , Exp Cell Res, 2018, Jun 1;367(1):73-80 PMID: 29571950
  • Jing Wang, .et al. , J Cell Sci, 2017, Mar 15; 130(6): 1078-1093 PMID: 28167680
  • Lessing D, .et al. , Proc Natl Acad Sci U S A, 2016, Dec 13;113(50):14366-14371 PMID: 28182563
  • Jennifer M. Sahni, .et al. , J Biol Chem, 2016, Nov 4; 291(45): 23756-23768 PMID: 27650498
  • Biological Activity
    Discription MLN8237 (Alisertib) is a selective Aurora A inhibitor with IC50 of 1.2 nM in a cell-free assay. It has >200-fold higher selectivity for Aurora A than Aurora B. Phase 3..
    Targets
    Target Value
    Product Information
    Catalog Num A10004
    Formula C27H20ClFN4O4
    Molecular Weight 518.9
    CAS Number 1028486-01-2
    SMILES COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 23 mg/mL (44.32 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 5%DMSO+30% PEG300+5%Tween-80+ddH2O 5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 19.27 mL 96.36 mL 192.72 mL
    0.5 mM 3.85 mL 19.27 mL 38.54 mL
    1 mM 1.93 mL 9.64 mL 19.27 mL
    5 mM 0.39 mL 1.93 mL 3.85 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    Keywords: buy MLN8237 (Alisertib) | MLN8237 (Alisertib) Supplier | purchase MLN8237 (Alisertib) | MLN8237 (Alisertib) cost | MLN8237 (Alisertib) manufacturer | order MLN8237 (Alisertib) | MLN8237 (Alisertib) distributor | buy 1028486-01-2 | 1028486-01-2 Supplier | purchase 1028486-01-2 | 1028486-01-2 cost | 1028486-01-2 manufacturer | order 1028486-01-2 | 1028486-01-2 distributor