MMV008138

Catalog No.: A19169

targeting antimalarial agent

MMV008138

MMV008138 Chemical Structure

CAS NO. 1679333-73-3

MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.

Availability: In stock

Package Price Qty
5 mg
$360.00
10 mg
$620.00
50 mg
$1,840.00
100 mg
$3,680.00
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Biological Activity

MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.68 mL 138.42 mL 276.84 mL
0.5 mM 5.54 mL 27.68 mL 55.37 mL
1 mM 2.77 mL 13.84 mL 27.68 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 361.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19169
M. Wt 361.22
Formula C18H14Cl2N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1679333-73-3
Synonyms MMV 008138, MMV-008138
SMILES O=C([[email protected]@H]1CC2=C([[email protected]@H](C3=CC=C(Cl)C=C3Cl)N1)NC4=C2C=CC=C4)O

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