MOR agonist-5 is a selective and potent mu-opioid receptor (MOR) agonist, exhibiting an EC50 of 0.25 nM. It demonstrates a significantly lower affinity for delta-opioid receptors (DOR) with an EC50 of 10 nM, and a negligible effect on kappa-opioid receptors (KOR) and nociceptin/orphanin FQ peptide receptors (NOR) at concentrations exceeding 10,000 nM. MOR agonist-5 displays substantial antinociceptive properties, making it a valuable tool for research into pain management and opioid receptor pharmacology.
MOR agonist-5 is a selective and potent mu-opioid receptor (MOR) agonist, exhibiting an EC50 of 0.25 nM. It demonstrates a significantly lower affinity for delta-opioid receptors (DOR) with an EC50 of 10 nM, and a negligible effect on kappa-opioid receptors (KOR) and nociceptin/orphanin FQ peptide receptors (NOR) at concentrations exceeding 10,000 nM. MOR agonist-5 displays substantial antinociceptive properties, making it a valuable tool for research into pain management and opioid receptor pharmacology.
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