MRS5663

Name: MRS5663
Brand: Adooq Bioscience
SKU: A57994
Rating: 5 (288 reviews)

Catalog No.: A57994

A3AR Agonist

MRS5663 is a potent A3 adenosine receptor (A3AR) agonist, demonstrating an EC50 of 5.62 nM in β-arrestin2 recruitment assays. This compound exhibits significant cytoprotective effects, particularly in models of skeletal muscle ischemia-reperfusion injury and claudication. Its unique mechanism and biological activity make it a valuable tool for research in cardiovascular and metabolic disorders.

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Biological Activity

Description	MRS5663 is a potent A3 adenosine receptor (A3AR) agonist, demonstrating an EC50 of 5.62 nM in β-arrestin2 recruitment assays. This compound exhibits significant cytoprotective effects, particularly in models of skeletal muscle ischemia-reperfusion injury and claudication. Its unique mechanism and biological activity make it a valuable tool for research in cardiovascular and metabolic disorders.

Product Information

Catalog Num	A57994
Formula	C22H21ClN6O3
Molecular Weight	452.89
CAS Number	1377272-66-6
SMILES	CNC1=NC(C#CC2=CC=CC=C2Cl)=NC3=C1N=CN3[C@@H]4[C@@H](C5)[C@]5(C(NC)=O)[C@@H](O)[C@H]4O

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