MRS7799 is a selective antagonist of the A3 adenosine receptor, demonstrating high affinity with Kds of 0.55 nM for human, 3.74 nM for mouse, and 2.80 nM for rat A3AR. This compound is particularly valuable in research applications related to neurodegeneration, cancer, and ischemic conditions in the heart and brain, as well as autoimmune inflammatory diseases. MRS7799 allows for the exploration of adenosine signaling pathways and their implications in various pathological states.
MRS7799 is a selective antagonist of the A3 adenosine receptor, demonstrating high affinity with Kds of 0.55 nM for human, 3.74 nM for mouse, and 2.80 nM for rat A3AR. This compound is particularly valuable in research applications related to neurodegeneration, cancer, and ischemic conditions in the heart and brain, as well as autoimmune inflammatory diseases. MRS7799 allows for the exploration of adenosine signaling pathways and their implications in various pathological states.
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