MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). This compound exhibits high selectivity for GPR68, minimizing off-target effects on related proton GPCRs, neurotransmitter transporters, and hERG ion channels. Additionally, MS48107 demonstrates the ability to effectively cross the blood-brain barrier in murine models, making it a valuable tool for neurobiological research and studies involving GPR68-related pathways.
MS48107 is a potent and selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68). This compound exhibits high selectivity for GPR68, minimizing off-target effects on related proton GPCRs, neurotransmitter transporters, and hERG ion channels. Additionally, MS48107 demonstrates the ability to effectively cross the blood-brain barrier in murine models, making it a valuable tool for neurobiological research and studies involving GPR68-related pathways.
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