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MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10 mL | 49.99 mL | 99.98 mL |
| 0.5 mM | 2 mL | 10 mL | 20 mL |
| 1 mM | 1 mL | 5 mL | 10 mL |
| 5 mM | 0.2 mL | 1 mL | 2 mL |
*The above data is based on the productmolecular weight 1000.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21929 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 1000.17 |
| Formula | C37H72N4O5S . 7/2C3H6O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1309370-86-2 |
| Synonyms | Trodusquemine lactate; Aminosterol-1436 lactate, MSI 1436, MSI1436 |
| SMILES | NCCCNCCCCNCCCN[[email protected]@H]1C[[email protected]@](C[[email protected]@H](O)[[email protected]]2([H])[[email protected]]3([H])CC[[email protected]@]4(C)[[email protected]@]2([H])CC[[email protected]@]4([[email protected]](C)CC[[email protected]@H](OS(=O)(O)=O)C(C)C)[H])([H])[[email protected]]3(C)CC1.O=C(O)C(C)O.[3.5] |
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