MT 63-78 is a specific and potent direct activator of AMP-activated protein kinase (AMPK), exhibiting an EC50 value of 25 μM. This compound not only induces cell mitotic arrest and apoptosis but also effectively inhibits prostate cancer growth through the suppression of lipogenesis and the mTORC1 signaling pathway. MT 63-78 demonstrates significant antitumor effects, making it a valuable reagent for cancer research applications focused on metabolic regulation and cell cycle modulation.
MT 63-78 is a specific and potent direct activator of AMP-activated protein kinase (AMPK), exhibiting an EC50 value of 25 μM. This compound not only induces cell mitotic arrest and apoptosis but also effectively inhibits prostate cancer growth through the suppression of lipogenesis and the mTORC1 signaling pathway. MT 63-78 demonstrates significant antitumor effects, making it a valuable reagent for cancer research applications focused on metabolic regulation and cell cycle modulation.
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