MTX-23 (PROTAC AR-V7 degrader-2)

Name: MTX-23 (PROTAC AR-V7 degrader-2)
Brand: Adooq Bioscience
SKU: A23932
Rating: 5 (288 reviews)

Catalog No.: A23932

PROTAC AR-V7 degrader

MTX-23 is an androgen receptor (AR)-targeting PROTAC that degrades both AR-FL and the splice variant AR-V7. It effectively inhibits prostate cancer cell proliferation and induces apoptosis, making it a promising tool for studying AR signaling and therapeutic resistance in prostate cancer.

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MTX-23 (PROTAC AR-V7 degrader-2) 2488296-74-6 PROTAC AR-V7 degrader

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Grouped product items
Size	Price	Stock
1mg	$117.00	In stock
5mg	$351.00	In stock
10mg	$598.00	In stock
50mg	$1,794.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	MTX-23 is an androgen receptor (AR)-targeting PROTAC that degrades both AR-FL and the splice variant AR-V7. It effectively inhibits prostate cancer cell proliferation and induces apoptosis, making it a promising tool for studying AR signaling and therapeutic resistance in prostate cancer.

Product Information

Catalog Num	A23932
Formula	C43H53F2N7O7S2
Molecular Weight	882.05
CAS Number	2488296-74-6
SMILES	O=C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)[C@H](C(C)(C)C)NC(CCCCNC(COC4=C(C5=CSC(N6CCOCC6)=N5)C=CC(F)=C4F)=O)=O
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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