Mu opioid receptor antagonist 7 is a potent antagonist of the µ-opioid receptor (µOR), demonstrating an IC50 value of 29 ± 3.0 nM. This compound is highly permeable to the central nervous system, making it suitable for investigating pain mechanisms and the pharmacology of opioid use disorder. Its efficacy in modulating µOR activity supports its use in preclinical research settings focused on opioid receptor signaling and related therapeutic interventions.
Mu opioid receptor antagonist 7 is a potent antagonist of the µ-opioid receptor (µOR), demonstrating an IC50 value of 29 ± 3.0 nM. This compound is highly permeable to the central nervous system, making it suitable for investigating pain mechanisms and the pharmacology of opioid use disorder. Its efficacy in modulating µOR activity supports its use in preclinical research settings focused on opioid receptor signaling and related therapeutic interventions.
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