Murayaquinone is a potent inhibitor of the β-catenin/Tcf4 complex, exhibiting an IC50 of 2.4 μM. This compound, derived from Streptomyces sp. AN140557, demonstrates significant nematicidal activity. It serves as a valuable tool for research applications focused on Wnt signaling pathways and their roles in developmental biology and cancer research.
Murayaquinone is a potent inhibitor of the β-catenin/Tcf4 complex, exhibiting an IC50 of 2.4 μM. This compound, derived from Streptomyces sp. AN140557, demonstrates significant nematicidal activity. It serves as a valuable tool for research applications focused on Wnt signaling pathways and their roles in developmental biology and cancer research.
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